in biology, we often draw enzymes and their substrates as shapes that just "fit" into each other, like a lock and key. in this class, we will instead draw the active sites and substrates of enzymes at a *molecular* level of detail, showing the individual atoms, the bonds between them, and how they interact and change as an enzyme performs its function. in particular, we will draw the chemical mechanism for how DNA polymerase synthesizes new DNA during DNA replication, as well as explain chemically why we need vitamin C to synthesize the collagen that connects our tissues. relevant organic chemistry background will be provided.